Description

The PRISM III score is an improved version of the PRISM score developed at the Children's National Medical Center in Washington, DC based on data collected at 32 pediatric intensive care units using 11,165 admissions.


Age Group

Age Range

neonate

0 to < 1 month

infant

1to 12 months

child

> 12 to 144 months (12 years)

adolescent

> 144 months (> 12 years)

 

Subscores:

(1) cardiovascular and neurologic vital signs: 5 measures

(2) acid-base and blood gas: 5 measures

(3) chemistry tests: 4 measures

(4) hematology tests: 3 measures (with PT and PTT counted as one)

 

Grading variables: Use the highest and/or lowest values for scoring.

 

Cardiovascular and Neurologic Vital Signs

Findings

Points

systolic blood pressure

neonate AND > 55 mm Hg

0

 

neonate AND 40 -55 mm Hg

3

 

neonate AND < 40 mm Hg

7

 

infant AND > 65 mm Hg

0

 

infant AND 45 -65 mm Hg

3

 

infant AND < 45 mm Hg

7

 

child AND > 75 mm Hg

0

 

child AND 55 -75 mm Hg

3

 

child AND < 55 mm Hg

7

 

adolescent AND > 85 mm Hg

0

 

adolescent AND 65 -85 mm Hg

3

 

adolescent AND < 65 mm Hg

7

heart rate

neonate AND < 215 beats/minute

0

 

neonate AND 215 - 225 bpm

3

 

neonate AND > 225 beats/minute

4

 

infant AND  < 215 beats/minute

0

 

infant AND 215 - 225 bpm

3

 

infant AND > 225 beats/minute

4

 

child AND < 185 beats/minute

0

 

child AND 185 - 205 bpm

3

 

child AND  > 205 beats/minute

4

 

adolescent AND < 145 beats/minute

0

 

adolescent AND 145 - 155 bpm

3

 

adolescent AND > 155 beats/minute

4

temperature

< 33°C

3

 

33 - 40°C

0

 

> 40°C

3

mental status

Glasgow coma score >= 8

0

 

Glasgow coma score < 8

5

pupillary response

both reactive

0

 

1 reactive AND (1 fixed AND > 3 mm)

7

 

both fixed AND both > 3 mm

11

 

where:

• The heart rate should not be monitored during crying or iatrogenic agitation.

• Pupillary size should not be assessed after iatrogenic dilatation.

• Body temperature may be rectal, oral, axillary or blood.

• Mental status should not be scored within 2 hours of sedation, paralysis or anesthesia. If sedation, paralysis or anesthesia is continuous, score based status prior to sedation, paralysis or anesthesia.

 

Acid-Base and Blood Gases

Findings

Points

acidosis

pH > 7.28 AND total CO2 >= 17 mEq/L

0

 

(pH 7.0 - 7.28) OR (total CO2 5 - 16.9 mEq/L)

2

 

pH < 7.0 OR total CO2 < 5

6

pH

< 7.48

0

 

7.48 - 7.55

2

 

> 7.55

3

PCO2

< 50 mm Hg

0

 

50 - 75 mm Hg

1

 

> 75 mm Hg

3

total CO2

<= 34 mEq/L

0

 

> 34 mEq/L

4

PaO2

>= 50 mm Hg

0

 

42.0 - 49.9 mm Hg

3

 

< 42 mm Hg

6

 

where:

• PaO2 requires arterial blood.

• PCO2 can be measured from arterial, venous or capillary specimens.

 

Chemistry Tests

Findings

Points

glucose

<= 200 mg/dL

0

 

> 200 mg/dL

2

potassium

<= 6.9 mEq/L

0

 

> 6.9 mEq/L

3

creatinine

neonate AND <= 0.85 mg/dL

0

 

neonate AND > 0.85 mg/dL

2

 

infant AND <= 0.90 mg/dL

0

 

infant AND > 0.90 mg/dL

2

 

child AND <= 0.90 mg/dL

0

 

child AND > 0.90 mg/dL

2

 

adolescent AND <= 1.30mg/dL

0

 

adolescent AND > 1.30 mg/dL

2

BUN

neonate AND <= 11.9 mg/dL

0

 

neonate AND > 11.9 mg/dL

3

 

not neonate AND <= 14.9 mg/dL

0

 

not neonate AND > 14.9 mg/dL

3

 

where:

• Whole blood measurements for glucose are increased 10% over serum; for potassium 0.4 mEq/L.

 

Hematologic Tests

Findings

Points

white blood cell count

>= 3,000 per µL

0

 

< 3,000 per µL

4

platelet count

> 200,000 per µL

0

 

100,000 - 200,000 per µL

2

 

50,000 - 99,999 per µL

4

 

< 50,000 per µL

5

PT and PTT

neonate AND PT <= 22 seconds AND PTT <= 85 seconds

0

 

neonate AND (PT > 22 seconds OR

neonate and PTT > 85 seconds)

3

 

not neonate AND PT <= 22 seconds AND PTT <= 57 seconds

0

 

not neonate AND (PT > 22 seconds OR PTT > 57 seconds)

3

 

where:

• The upper limit of the normal reference ranges for PT and PTT are not given.

 

Other factors to document:

(1) nonoperative cardiovascular disease

(2) chromosomal anomaly

(3) cancer

(4) previous ICU admission during current admission

(5) pre-ICU CPR during current admission

(6) post-operative (not including catheterizations) during past 24 hours

(7) acute diabetes with ketoacidosis or other severe complication

(8) admission from inpatient unit (do not count if in ICU for < 2 hours or if transferred from surgical recovery room)

 

cardiovascular and neurologic subscore =

= (points for systolic pressure) + (points for temperature) + (points for mental status)+ (points for heart rate) + (points for pupillary reflex)

 

acid-base and blood gas subscore =

= (points for acidosis) + (points for pH) + (points for PaCO2)+ (points for total CO2) + (points for PaO2)

 

chemistry subscore =

= (points for glucose) + (points for potassium) + (points for creatinine)+ (points for blood urea nitrogen)

 

hematology subscore =

= (points for WBC count) + (points for platelet count) + (points for PT and PTT testing)

 

total PRISM III score =

= (cardiovascular and neurologic subscore) + (acid base and blood gas subscore) + (chemistry subscore)+ (hematology subscore)

 

Interpretation:

• minimum subscore and total score: 0

• maximum cardiovascular and neurologic subscore: 30

• maximum acid-base and blood gas subscore: 22

• maximum chemistry subscore: 10

• maximum hematology subscore: 12

• maximum total PRISM III score: 74

• The higher the total score, the worse the prognosis.

• A rising score indicates deterioration.

• If performed during the first 12 hours in the ICU, the score is designated PRISM-12.

• If performed during the first 24 hours in the ICU, it is designated PRISM-24.

 

Predictive equations:

• Predictive equations for prognosis are available for the 12 hour and 24 hour scores.

• The equations for predicting prognosis from total score are patented and unpublished but can be obtained for research purposes from the authors.


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