Predictors of Kudo et al for Delayed Encephalopathy in a Person with Acute Carbon Monoxide Poisoning

 

Patient selection: admitted for acute carbon monoxide poisoning

 

Direct measures of carbon monoxide toxicity:

(1) unrousable despite noxious stimuli (Japanese Coma Score or JCS >= 100) on admission

(2) brain CT or MRI changes of hypoxic encephalopathy

(3) elevated serum enzyme concentrations (CK, LDH)

(4) psychiatric disability by the Global Assessment Scale (GAS)

 

Indirect measures of carbon monoxide toxicity:

(1) high number of hyperbaric oxygen therapy sessions (> 20 sessions)

(2) prolonged hospitalization (> 60 days)