Predictors of Fu et al For Overall Survival Following a First Admission to the Intensive Care Unit for a Patient with Advanced Cancer

 

Patient selection: advanced cancer referred to a Phase I clinical trials program. Entry into a Phase I clinical trial requires advanced cancer that is refractory to standard therapy or for which there is no effective standard therapy that will increase survival for >= 3 months.

 

Predictors of a poor overall survival after the ICU admission:

(1) NOT (following a surgical intervention)

(2) hypoalbuminemia

(3) higher APACHE II score on ICU admission (>= 18)

(4) need for cardiopulmonary resuscitation (CPR) and/or mechanical ventilation

 

Although long-term survival is rare for this group of patients, these risk factors can help to identify a group for whom survival is short.