Patient selection: age >= 18 years, admitted to a medical ICU for > 24 hours
Exclusion: arrhythmia prior to ICU admission, surgical patient, history of ICU admission in past 90 days, transfer from an ICU outside of institution
Outcome: 60-day mortality after ICU admission (page 525)
Predictors from multivariate analysis:
(1) APACHE II score based on worst variables during first 24 hours after admission
(adjusted odds ratio 1.06 per point, maximum 71 points))
(2) new-onset atrial fibrillation (adjusted OR 1.99)
(3) septic shock (adjusted OR 2.78)
(4) continuous renal replacement therapy (adjusted odds rati 2.93)
cumulative product of adjusted odds ratio for mortality =
= PRODUCT(adjusted odds ratios for predictors)
Interpretation:
• minimum cumulative product: 1
• maximum cumulative product:1,015
• The higher the cumulative product of AOR the greater the 60-day mortality.
