Fu et al evaluated the impact of thrombolytic parameters on 1-year mortality following percutaneous coronary intervention (PCI). The authors participated in the ASSENT-2 trial.
Parameters:
(1) time to treatment in hours
(2) percent resolution of ST elevation at 24 to 36 hours after fibrinolysis
Time to Treatment |
Percent Resolution |
1-Year Mortality Rate |
< 2 hours |
>= 70% |
3.8% |
|
30 to 69% |
5.7% |
|
0 to 29% |
7.3% |
2 to 4 hours |
>= 70% |
5.2% |
|
30 to 69% |
8.4% |
|
0 to 29% |
8.7% |
> 4 hours |
>= 70% |
6.6% |
|
30 to 69% |
9.9% |
|
0 to 29% |
13% |
where:
• 70-100% resolution in ST elevation indicates complete ST elevation resolution. 30-69% indicates partial resolution. Less than 30% indicates no resolution.
In Figure 7 the line for percent ST rsolution at 24 to 36 hours after fibrinolysis versus 1 year mortality rate:
1-year mortality rate in percent =
= (-0.05695 * (percent resolution)) + 11
Specialty: Cardiology