Description

Niskanen et al developed 2 models based on logistic regression to predict in-hospital mortality for patients admitted to the intensive care unit (ICU) as a result of a gastroenterologic emergency. This can help identify patients who may benefit from more aggressive interventions. The authors are from 6 university hospitals in Finland.


 

Parameters

Model A

Model B

APS on day 1

0.164 * APS

0.143 * APS

TISS on day 1

0

0.041 * TISS

age in years

0.030 * age

0.030 * age

postoperative admission

add 0.076

add -0.097

liver disease present

add 0.944

add 0.938

cardiovascular disease present

add 0.559

add 0.672

respiratory disease present

add 0.416

add 0.441

renal disease present

add -0.216

add -0.104

immunocompromised state present

add 0.674

add 0.560

gastrointestinal bleeding present

add 0.364

add 0.423

sepsis present

add 0.690

add 0.555

neoplasm present

add 0.659

add 0.751

respiratory insufficiency after surgery

add -0.563

add -0.492

hemorrhagic shock present

add -0.292

add -0.470

bowel perforation or obstruction present

add -0.061

add -0.084

constant

-4.217

-5.088

 

 

where:

• The Acute Physiology Score (APS) was calculated from APACHE II.

 

A =

= SUM(items present in Model A)

 

B =

= SUM(items present in Model B)

 

probability for in-hospital death using Model A =

= 1 / (1 + EXP((-1) * A))

 

probability for in-hospital death using Model B =

= 1 / (1 + EXP((-1) * B))

 

Performance:

• The ROC plots show both models to be slightly better than APACHE II (Figure 3, page 591).

• The addition of TISS in Model B did not provide much benefit.

 

Limitations:

• The authors point out that the results of the calculations should be used with caution since the number of patients was too low to guarantee the accuracy for the outcome prediction.


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