A patient may develop a nongranulomatous uveitis following an infection with Group A Streptococcus (Streptococcus pyogenes).
Clinical findings:
(1) recent infection with Group A Streptococcus
(2) bilateral ocular involvement
(3) reduced visual acuity
The patient may develop:
(1) anterior uveitis
(2) variable involvement of the posterior segment (vitritis, choroiditis, swelling of the optic disc, focal retinitis)
(3) panuveitis
Other complications associated with the poststreptococcal syndrome may include:
(1) reactive arthritis
(2) erythema nodosum
(3) glomerulonephritis
Making the diagnosis:
(1) exclusion of other causes
(2) serologic evidence of a recent streptococcal infection (anti-streptococcal lysine O/ASO, anti-deoxyribonuclease B)
(3) recurrence with subsequent episodes of Group A streptococcal infections
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Specialty: Ophthalmology, Infectious Diseases, Immunology/Rheumatology