Pneumocystis Pneumonia | Model to Predict Mortality in AIDS Patient in ICU

 

Patient selection: AIDS with respiratory failure secondary to Pneumocystis pneumonia

 

Elements of the modified multisystem organ failure score (from that of Bihari et al)

(1) respiratory failure

(2) cardiovascular failure

(3) renal failure

(4) hepatic failure

(5) hematologic failure

(6) gastrointestinal tract bleeding

(7) encephalopathy before intubation

The presence of each was worth one point. The MOFS was the sum of these and ranged from 0 to 7.

 

Serum LDH had a normal range of 300 to 550 IU/L. A value >= 2000 IU/L (3.6 times upper limit of normal) was considered positive and was assigned 1 point.

 

total score =

= (points for MOFS) + (points for serum LDH)

 

Interpretation:

• minimum total score: 0 (in practice the minimum would be 1 or the person would not be in the ICU with respiratory failure)

• maximum total score: 8

• The higher the score the greater the risk for patient mortality.

Total Score	Mortality Rate
1	36%
2	68%
3	80%
4 to 8	100%