Patient selection: adult with a lymphoid malignancy
Parameters:
(1) body weight of the patient
(2) number of CD34+ cells infused
(3) number of nucleated cells infused
(4) number of umbilical cord blood units infused
If the number of CD34+ cells was > 100,000 per kg body weight, then the odds ratio for neutrophil engraftment was 2.7.
If the total number of nucleated cells was > 2 * 10^7 per kg body weight, then
(1) non-relapse related mortality was improved.
(2) progression free survival was improved.
(3) overall survival was improved.
If a double umbilical cord blood unit was infused then relapse or progression were significantly reduced (OR 0.28).
