Sharathkumar et al developed a decision rule for predicting the risk of venous thromboembolism in a hospitalized child. The authors are from Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Riley Hospital for Children, and Indiana University.
Patient selection: hospitalized pediatric patient (age range 0 to 20 years)
Outcome: venous thromboembolism
Parameters:
(1) length of stay in days
(2) direct admission to ICU
(3) central venous catheter
(4) blood stream infection
(5) immobilization
(6) birth control pills (BCP)
Parameters
Findings
Points
length of stay in days
< 7
0
>= 7
2
direct admission to ICU
no
0
yes
0.5
central venous catheter
no
0
yes
1
blood stream infection
no
0
yes
1
immobilization
no
0
yes
3
birth control pills
no
0
yes
2
total score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 9.5
• A score >= 3 indicates a high risk for venous thromboembolism.
Performance at cutoff:
• Sensitivity 70%, specificity 80%, AUC 0.85.
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