Outcomes of Thakkar et al for a Patient with Acute Leukemia Admitted to the ICU

 

Common reasons for admission to the ICU:

(1) infection or fever

(2) respiratory failure

(3) hypotension

 

Predictors of a poor outcome:

(1) poor risk cytogenetics

(2) higher APACHE II score on admission (median score was 22; will use >= 15 in the implementation)

(3) need for vasopressors

(4) recent preparation regimen for bone marrow transplantation

 

Factors associated with 12 month survival (Figure 2, page 2239):

(1) need for pressors

(2) intubation (implies respiratory failure)

 

Need for Pressors	Intubation	Survival at 1 Year
no	no	33-37%
no	yes	11-12%
yes	no	13-17%
yes	yes	3-4%

 

where:

• The original table includes duration of ICU stay < 7 vs >= 7 days.

• The table could be further compressed by have 0, 1 or 2 of the risk factors.

• The group with the best outcome may not have needed to be admitted to the ICU.