A patient with generalized myasthenia may have ocular findings, but ocular myasthenia should be largely limited to the eyes.
A patient may present initially with ocular myasthenia, only to progress to generalized involvement over time (conversion).
Ocular involvement may include:
(1) ocular pain
(2) blurred vision
(3) tearing
(4) ptosis, which may deteriorate during the day
(5) diplopia
Ocular MG may be associated with other autoimmune diseases, such as:
(1) autoimmune thyroiditis
(2) inflammatory bowel disease (Crohn’s disease, ulcerative colitis)
(3) SLE
(4) lichen planus
Autoantinbodies may be present which may be associated with a concurrent autoimmune disorder:
(1) antibody to acetylcholine receptor
(2) antibody to smooth muscle
(3) p-ANCA
