Description

Bessell et al developed a score for predicting outcome in a patient with primary non-Hodgkin's lymphoma affecting the central nervous system (CNS). The authors are from Nottingham City Hospital in England and the University of Barcelona in Spain.


Parameters:

(1) age of the patient in years

(2) ECOG performance scale

(3) extent of disease

 

Parameter

Finding

Points

age of the patient

< 60 years

0

 

>= 60 years

1

ECOG performance

0 or 1

0

 

2, 3 or 4

1

extent of disease

multifocal and/or meningeal disease (advanced stage)

1

 

unifocal, nonmeningeal disease

0

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the worse the clinical outcome.

 

Total Score

Median Survival

0

55 months

1

41 months

2

32 months

3

1 month

 


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