The staging system for myeloma of the Southeastern Cancer Study Group is similar to that of Carbone et al, except that the Karnofsky performance index is used.
A "poor risk" if one or more of the following are present:
(1) hemoglobin < 9 g/dL
(2) serum calcium > 12 mg/dL
(3) Karnofsky performance status < 60%
(5) BUN > 30 mg/dL
Parameter |
Finding |
Points |
hemoglobin |
>= 9 g/dL |
0 |
|
< 9 g/dL |
1 |
serum calcium |
<= 12 mg/dL |
0 |
|
> 12 mg/dL |
1 |
Karnofsky performance status |
>= 60% |
0 |
|
< 60% |
1 |
BUN |
<= 30 mg/dL |
0 |
|
> 30 mg/dL |
1 |
number of poor risk factors =
= SUM(points for all 4 parameters)
Interpretation:
• minimum number of poor risk factors: 0
• maximum number of poor risk factors: 4
Poor Risk Factors |
Survival in Months |
none |
16 +/- 4.2 |
1 or more |
6.3 +/- 2.2 |
Specialty: Hematology Oncology
ICD-10: ,