Performance status (ECOG):
(0): asymptomatic with no clinical evidence of disease (Karnofsky index 100)
(1): symptomatic but able to continue normal work and activities (Karnofsky index 80-90)
(2): too ill to work but able to care for self, with less than 50% of time in bed (Karnofsky index 60-70)
(3): requires considerable assistance and frequent medical care, with more than 50% of time spent in bed (Karnofsky index 50)
(4): severely disabled, requires hospitalization and active supportive treatment, with > 95% of time spent in bed (bedridden; Karnofsky index < 50)
Risk factors associated with worse survival:
(1) hemoglobin < 9 g/dL
(2) blood urea nitrogen > 30 mg/dL
(3) serum calcium is > 12 mg/dL
(4) performance status 2, 3 or 4
where:
• conversion of BUN from mg/dL to mmol/L is 0.357; from mmol/L to mg/dL is 2.80112
• conversion of calcium from mg/dL to mmol/L is 0.25; from mmol/L to mg/dL is 4.0
|
Number of Risk Factors
|
Survival
|
|
0
|
25 months
|
|
1
|
18 months
|
|
2
|
14.5 months
|
|
3 or 4
|
5.5 months
|
