Multiple Organ Failure Score of Goris et al

pulmonary

no mechanical ventilation

0

mechanical ventilation with a positive end expiratory pressure (PEEP) of <= 10 cm H2O and an FIO2 <= 0.4

1

mechanical ventilation with PEEP > 10 cm H2O and/or FIO2 > 0.4

2

cardiac

normal blood pressure with no vasoactive substances necessary

0

periods with hypotension necessitating manipulations such as volume loading to keep blood pressure above 100 mm Hg, dopamine HCl infusion <= 10 µg/kg/min, or nitroglycerin <= 20 µg/min

1

periods with hypotension below 100 mm Hg, dopamine HCl infusion > 10 µg/kg/min, or nitroglycerin > 20 µg/min

2

renal

serum creatinine < 2 mg/dL

0

serum creatinine >= 2 mg/dL

1

hemodialysis or peritoneal dialysis required

2

hepatic

SGOT < 25 U/L and total bilirubin < 2 mg/dL

0

SGOT >= 25 U/L and < 50 U/L, and/or total bilirubin >= 2 mg/dL and < 6 mg/dL

1

SGOT >= 50 U/L and/or bilirubin >= 6 mg/dL

2

hematologic

normal WBC and platelet counts

0

platelet count <= 50,000 per µL and/or WBC count >=30,000 and < 60,000 per µL

1

hemorrhagic diathesis and/or a WBC count < 2,500 per µL or >= 60,000 per µL

2

gastrointestinal tract

normal functioning

0

acalculous cholecystitis or stress ulcer

1

bleeding from stress ulcer necessitating transfusion of more than 2 units of blood per 24 hours, necrotizing enterocolitis, pancreatitis, and/or spontaneous perforation of the gallbladder

2

central nervous system

normal functioning

0

clearly diminished responsiveness

1

severely disturbed responsiveness and/or diffuse neuropathy

2