Description

Santoro et al developed a nomogram for predicting the likelihood of a local or systemic complication following surgery for a cancer of the oral cavity or oropharynx. These can help to identify a patient who may benefit from more aggressive management. The authors are from the European Institute of Oncology in Milan and San Matteo Hospital in Pavia, Italy.


 

Patient selection: cancer of oral cavity or oropharyngeal cancer

 

Outcome: local or systemic complications

 

Parameter:

(1) alcohol

(2) tumor site

(3) clinical T score and gender

(4) neck dissection

 

Parameter

Finding

Points

alcohol

no

0

 

former

46.3

 

current

46.3

tumor site

oral cavity

0

 

oropharynx

41.3

clinical T stage and gender

cT0 to cT3 and female

17.3

 

cT4 and female

0

 

cT0 to cT3 and male

20

 

cT4 and male

100

neck dissection

no

0

 

unilateral or bilateral

80.3

 

total score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 268

• The greater the score the greater the risk of a local or systemic complication.

Total Score

Percent Likelihood of a Postoperative Complication

< 14

< 14%

14 to 167

(0.00065 * ((points)^2)) + (0.2554 * (points)) + 9.585

167 to 268

(-0.001233 * ((points)^2)) + (0.767 * (points)) - 23.68

 

Performance:

• Area under the ROC curve 0.74.

 


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