Description

Pohlen et al developed a model for predicting mortality for a patient with acute myeloid leukemia (AML) who has been discharged from the ICU. This can help to identify a patient who may benefit from admission to the ICU. The authors are from University Hospital Muenster in Germany.


 

Patient selection: AML admitted to ICU

 

Outcome: mortality after discharge from ICU

 

Parameters:

(1) AML disease status

(2) allogeneic stem cell transplant

(3) days in the hospital before the ICU admission

(4) days spent in the ICU

(5) urine production at ICU admission

(6) Glasgow coma score at ICU admission

(7) hematocrit at ICU admission

 

Parameter

Finding

Points

AML disease status

newly diagnosed

0

 

in remission

0

 

refractory (advanced)

1.886

 

relapsed (advanced)

1.886

allogeneic stem cell transplant

no

0

 

yes

0.974

days in the hospital before

 

<days> * 0.036

days in the ICU

 

<days> * (-0.055)

urine output at ICU admission

>= 1,000 mL per 24 hours

0

 

< 1,000 mL per 24 hours

1.789

Glasgow coma score

>= 8

0

 

< 8

1.465

hematocrit

>= 25%

0

 

< 25%

(-1.51)

 

total score =

= SUM(points for all 7 parameters)

 

Total Score

Risk Group

1-Year Survival

< 0.23

low

100%

0.23 to 2.33

intermediate

82%

> 2.33

high

42%

 


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