Description

Miniati et al developed a model for predicting the probability of a pulmonary embolism in a patient. This can separate patients into low and high risk groups. The authors are from Universita degli Studi di Firenze, University of South Carolina, and Instituto di Fisiologia Clinica del Consiglio Nazionale Dell Ricerche in Pisa, Italy.


 

Parameters:

(1) age of the patient in years

(2) gender

(3) immobilization

(4) history of deep vein thrombosis

(5) preexisting cardiovascular disease

(6) preexisting pulmonary disease

(7) sudden onset of dyspnea

(8) orthopnea

(9) chest pain

(10) fainting or syncope

(11) hemoptysis

(12) unilateral leg swelling

(13) body temperature

(14) wheezes on chest auscultation

(15) crackles on chest auscultation

(16) acute cor pulmonale on ECG

Parameter

Finding

Points

age

< 57 years of age

0

 

57 to 67 years

0.80

 

68 to 74 years

0.87

 

>= 75 years

1.14

gender

female

0

 

male

0.60

immobilization

absent

0

 

present

0.42

history of deep vein thrombosis

absent

0

 

present

0.64

cardiovascular disease

absent

0

 

present

-0.51

pulmonary disease

absent

0

 

present

-0.89

sudden onset of dyspnea

absent

0

 

present

2.0

orthopnea

absent

0

 

present

-1.51

chest pain

absent

0

 

present

1.01

fainting or syncope

absent

0

 

present

0.66

hemoptysis

absent

0

 

present

0.93

unilateral leg swelling

absent

0

 

present

0.80

body temperature

<= 38°C

0

 

> 38°C (febrile)

-1.47

wheezes

absent

0

 

present

-1.20

crackles

absent

0

 

present

-0.61

acute cor pulmonale on ECG

absent

0

 

present

1.96

 

where:

• ECG changes of acute cor pulmonale include one or more of the following: S1Q3T3, S1S2S3, negative T waves in right precordial leads, transient right bundle branch block, and/or pseudoinfarction.

 

X =

= SUM(points for all 16 parameters) - 3.43

 

probability of a pulmonary embolism =

= 1 / (1 + EXP((-1) * X))

 


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