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Model of Kamali et al for Determining Warfarin Dose in a Patient Based on CYP2C9 Genotype

Purpose:

To estimate a patient's daily dose of warfarin using the model of Kamali et al.

Specialty:

Cardiovascular Diseases, Vascular Medicine, Clinical Pharmacology, Pharmaceutical Medicine

Objective:

dosage calculations

ICD-10:

I74, I81, I82, O88, T79.0, T79.1

Description:

Kamali et al compared the dose of warfarin for a patient and various characteristics including the CYP2C9 genotype. This can help determine the kinetics of the drug and to ensure accurate dosing. The authors are from the University of Newcastle, Royal Victoria Infirmary and the Freeman Hospital in Newcastle upon Tyne, England.

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