For adults aged 20-80 with stable renal function, then the creatinine clearance can be estimated from the gender, serum creatinine and age in years.
estimated creatinine clearance for males =
= ((98 - (16/20 * (age - 20))) / (serum creatinine in mg/dL)) mL/min per 1.73 meters-squared =
= ((98 - (0.8 * (age - 20))) / (serum creatinine in mg/dL)) mL/min per 1.73 meters-squared
estimated creatinine clearance for females =
= 90% of that predicted for males =
= (0.9 * (98 - (0.8 * (age - 20))) / (serum creatinine in mg/dL)) mL/min per 1.73 meters-squared
where:
• The age is taken to nearest decade.
• It is uses the assumption that the average body surface area for 70 kg male is 1.73 meters-squared.
Limitations:
• The equation cannot be used if muscle mass is significantly different from the average (for example, as in cachexia or in the excessively muscular)
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Specialty: Nephrology, Clinical Laboratory
