Description

Many types of porphyria are associated with photosensitivity. The amount of circulating porphyrin impacts the severity and duration of the skin reactions.


 

Conditions with skin lesions only:

(1) porphyria cutanea tarda (PCT)

(2) congenital erythroietic porphyria (CEP)

(3) hepatoerythropoietic porphyria (HEP)

(4) erythropoietic protoporphyria (EPP)

 

Conditions with neurovisceral symptoms in addition to skin lesions:

(1) hereditary coproporphyria (HCP)

(2) variegate porphyria (VP)

 

The patient may also experience bullae and skin fragility. In erythropoietic protoporphyria the patient may develop urticaria.

 

Management:

(1) Discontinue any drug contributing to porphyrin overproduction (and identify a safe substitute if essential).

(2) Avoid alcohol.

(3) Maintain an adequate diet and hydration.

(4) Avoid sunlight and bright lights.

(5) Cover the skin with clothing and/or a barrier cream.

 


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