Description

Most patients with sarcoidosis present as young or middle-aged adults. Some patients present at an older age.


 

Criteria for the diagnosis of late-onset sarcoidosis:

(1) The patient has clinical sarcoidosis.

(2) The onset of the disease is >= 65 years of age.

(3) The patient has not been diagnosed with sarcoidosis in the past.

(4) A biopsy shows non-caseating granulomas OR the patient has Lofgren's syndrome.

(5) No other diagnosis can explain the findings better.

 

Late-onset sarcoidosis is more common in women than men.

 

An accessory salivary gland is a convenient site to biopsy.

 

A patient with late-onset sarcoidosis may show:

(1) asthenia

(2) uveitis

(3) specific skin lesions

 

A patient with late-onset sarcoidosis is less likely than a younger patient to show:

(1) erythema nodosum

(2) asymptomatic chest X-ray findings

 


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