Chemical analysis of the sputum from a patient with chyloptysis can support the diagnosis.
An early morning specimen is recommended.
Features of sputum in chyloptysis on chemical analysis:
(1) The triglyceride concentration is often >= 250 mg/dL.
(2) The cholesterol concentration is often < 50 mg/dL but may be higher if the triglyceride concentration is very high.
(3) The ratio of cholesterol to triglyceride concentration is < 0.10.
(4) Chylomicrons are present on lipoprotein electropheresis.
Features of the sputum on smear exam:
(1) The fluid is acellular (exception: inflammatory cells during period of infection).
(2) The lipid material stains with Sudan III.
