Many patients with Klinefelter's Syndrome (KS) go undiagnosed. Kamischke et al listed a number of criteria which can help to identify a man who should have a more complete evaluation. The authors are from the University of Muenster in Germany.
Screening criteria:
(1) infertility with small testicular volume AND azoospermia
(2) elevated serum LH and FSH concentrations
(3) Barr body present
A patient suspected of having Klinefelter's syndrome should undergo further evaluation to confirm or exclude the diagnosis.
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