Description

Jimson weed is a North American plant associated with an anticholinergic syndrome if injested or smoked. It was used by the Indians for religious and medicinal purposes.


 

Plant name: Datura stramonium

 

Synonyms: thorn apple, Jamestown weed, angel's trumpet

 

Active ingredients: atropine, scopolamine, hyoscyamine

 

Toxic parts of plant: all

 

Exposures may involve:

(1) seeds

(2) roots (brewed into a tea)

(3) leaves

 

Clinical findings:

(1) agitation

(2) visual, tactile and/or auditory hallucinations (which may involve insects)

(3) mydriasis, blurred vision and/or photophobia

(4) tachycardia

(5) dry mouth

(6) nausea and vomiting

(7) incoherence

(8) disorientation and confusion

(9) combativeness

(10) slurred speech

(11) urinary retention

(12) decreased bowel motility (which prolongs the absorption; associated with reduced bowel sounds)

(13) thirst

(14) difficulty swallowing

(15) hyperthermia

(16) seizures

(17) reduced level of consciousness, including coma

 

An excessive exposure can result in death.

 

The average seed contains 0.1 mg of atropine per seed. A lethal dose of atropine for an adult is around 10 mg (approximately 100 seeds). In the report from CDC persons presenting with serious intoxication had ingested from 30-50 seeds.

 


To read more or access our algorithms and calculators, please log in or register.