Barbui et al reported the International Prognostic Score for thrombosis in Essential Thrombocythemia (IPSET-thrombosis). The authors are from multiple hospitals in Europe and the Mayo Clinic.
NOTE The IPSET of Passamonti et al is discussed in Chapter 28.
Patient selection: essential thrombocythemia (ET) using the WHO criteria.
Parameters:
(1) age in years
(2) cardiovascular risk factors (smoking, diabetes, hypertension)
(3) history of previous thrombosis
(4) JAK2V617F mutation
|
Parameters |
Findings |
Points |
|
age in years |
<= 60 years of age |
0 |
|
|
> 60 years of age |
1 |
|
cardiovascular risk factors |
no |
0 |
|
|
yes |
1 |
|
history of previous thrombosis |
no |
0 |
|
|
yes |
2 |
|
JAK2V617F |
no |
0 |
|
|
yes |
2 |
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• The higher the score the greater the risk for thrombosis.
|
Total Score |
Risk Group |
|
0 or 1 |
low |
|
2 |
intermediate |
|
3 to 6 |
high |
Specialty: Hematology Oncology, Clinical Laboratory
ICD-10: ,
