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Integrated Index of Gobbi et al for Patients with Advanced Hodgkin's Disease

Description

Gobbi et al evaluated the different prognostic scores for patients with advanced Hodgkin's disease. They developed an integrated index for combining the scores of Straus et al (1990), Gobbi et al (1994) and Hasenclever and Diehl (1998) into a single predictive instrument. The authors are from multiple university hospitals in Italy.


 

NOTE: In 2001 a program could be downloaded to perform these calculations at www.unimo.it/gisl/default.htm

Scores for Inclusion

Data for Inclusion

Straus et al (28.08.07)

group from 0 to 5

Gobbi et al (Integrated Database on Hodgkin's Disease; 28.08.05)

probability of surviving 120 months (10 years), as a decimal fraction

Hasenclever and Diehl (International Prognostic Factors Project; 28.08.01)

group from 0 to 7

 

integrated index =

= (0.950 * (probability of Gobbi to survive 120 months)) + (0.541 * (group from Straus model)) – (0.302 * (group from Hasenclever and Diehl))

 

Interpretation:

• minimum index: theoretically –2.1

• maximum index: theoretically 3.45

 

Integrated Index

Probability of Survival at 10 Years (120 Months)

Percent Cumulative Risk

< -0.90

88%

10%

-0.90 to –0.25

80%

18%

-0.25 to 0.15

65%

29%

0.15 to 1.05

43%

52%

> 1.05

< 40%

69%

from Figure 3, page 1476

 


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