A patient with Klinefelter's syndrome may have reduced fertility and sexual dysfunction.
Factors contributing to subfertility:
(1) fibrosis and hyalinization of the seminiferous tubules
(2) decreased and abnormal sperm production
Factors contributing to hypogonadism and impaired sexual function:
(1) decreased serum testosterone
(2) elevated serum gonadotropins (FSH, LH)
Manifestations of hypogonadism:
(1) small testes
(2) sparse hair
(3) gynecomastia
Impaired sexual function may include:
(1) decreased libido
(2) erectile dysfunction
(3) impaired ejaculation
Modern fertility methods can retrieve sufficient sperm for in vitro fertilization but there is an increased risk for chromosomal defects.
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Specialty: Urology, Clinical Laboratory
ICD-10: ,
