Indications for Starting Therapy in a Patient with Known or Suspected Methanol Poisoning

 

A person should be treated for methanol poisoning if one or more of the following are present:

(1) plasma methanol concentration >= 6.2 mmol/L (>= 20 mg/dL)

(2) both of the following:

(2a) documented exposure of methanol

(2b) osmolal gap > 10 mOsm per kg water

(3) both of the following:

(3a) suspected exposure of methanol

(3b) 2 or 3 of the following:

(3b1) osmolal gap > 10 mOsm per kg water

(3b2) serum total carbon dioxide concentration < 20 mmol/L (metabolic acidosis)

(3b3) arterial pH < 7.3