Hazards of Other Medications Ingested During the Abuse of an Over-the-Counter (OTC) Medication

Description

Over-the-counter (OTC) medications may contain compounds that can be abused. However, the levels or potency of these is such that large quantities must be taken to get any effect. If someone takes enough of these products to become intoxicated, then they may have co-ingested other compounds that can be hazardous to their health.

Desired compound:

(1) ethanol

(2) phenylephrine, L-methamphetamine (Vicks inhaler) or other decongestant

(3) dextromethorphan

Compound Also Ingested	Adverse Effects
acetaminophen	toxic hepatitis (see above)
caffeine	agitation
chlorpheniramine maleate or other anticholinergic agent	tachycardia, mydriasis, urinary retention, seizures, depressed level of consciousness, flushed skin (anticholinergic syndrome)
bromide	gastrointestinal complains, depressed level of consciousness, ataxia, tremors, mania, confusion, depression, hallucinations (bromism, see chapter 33)
vitamins	hypervitaminosis A
diphenhydramine (Benadryl)	sedation or paradoxical agitation
acetylsalicylic acid or an NSAID	GI bleeding

Many people consider OTC products to be harmless. It is always important to read the hazard warnings on an OTC product and not to exceed the limits on their use.

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Description

Specialty

ICD-10