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Risk of Hair Loss Associated with Chemotherapeutic Agents

Purpose: To identify a chemotherapeutic regimen that may be associated with alopecia.

Description

Hair loss may be distressing for a patient undergoing chemotherapy. The risk of alopecia depends on a number of factors, including which chemotherapeutic drugs are given.


 

Other factors affecting the risk of alopecia:

(1) number of chemotherapeutic agents

(2) duration and dose of therapy

(3) concurrent radiation therapy

(4) age

(5) comorbid conditions such as malnutrition or graft-vs-host disease

Risk Level

Hair Loss

3

usually causes, common

2

sometimes causes

1

uncommon

 

 

Drug

Risk of Hair Loss

5-flurouracil (5-FU)

2

6-mercaptopurine

1

actinomycin D

2

adriamycin

3

amsacrine

2

bleomycin

2-3

busulphan

2

capecitabine

1

carboplatin

1

carmustine

1

chlorambucil

2

cisplatin

1

cyclophosphamide

3

cytarabine

2

daunorubicin

3

docetaxel

3

doxorubicin

3

epirubicin

3

etoposide

3

floxuridine

2

fludarabine

1

gemcitabine

2

hydroxyurea

2

idarubicin

3

ifosfamide

3

irinotecan

3

lomustine

2

mechlorethamine (nitrogen mustard)

2-3

mercaptopurine

2

methotrexate

1-2

mitomycin C

1

mitoxantrone

1-2

paclitaxel

3

procarbazine

1

raltritrexate

1

streptozotocin

1

teniposide

2

thiotepa

2

topotecan

3

vinblastine

2 (may be severe)

vincristine

2 (may be severe)

vindesine

3

vinorelbine

2-3

 


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Specialty

Objective

ICD-10