The International Bone Marrow Transplant Registry (IBMTR) modified the Glucksberg scheme for grading acute graft-versus-host disease (GVHD). It is similar to the Glucksberg scheme, but does not use subjective assessment of performance.
IBMTR Index |
Criteria |
0 |
• no GVHD (reference population) |
A |
• Stage 1 skin involvement only |
B |
• Stage 2 skin involvement only • Stage 0 - 2 skin involvement with Stage 1-2 liver and/or Stage 1-2 gastrointestinal involvement |
C |
• Stage 3 skin, liver, and/or gut involvement |
D |
• Stage 4 skin, liver, and/or gut involvement |
IBMTR Index |
Relative Risk for Treatment Failure |
95% Confidence Interval |
A |
0.85 |
0.69 - 1.05 |
B |
1.21 |
1.02 - 1.43 |
C |
2.19 |
1.78 - 2.71 |
D |
5.69 |
4.57 - 7.08 |
where:
• relative risk is based on that seen in the reference population without acute GVHD
Purpose: To use the IBMTR grading scheme to evaluate a patient with acute graft-versus-host disease (GVHD).
Specialty: Immunology/Rheumatology, Surgery, general
Objective: laboratory tests, disease progression, complication detection
ICD-10: T86,