A patient with AIDS may develop a sclerosing cholangitis secondary to one or more causes.
Potential causes:
(1) cytomegalovirus (CMV)
(2) Cryptosporidium
(3) Microsporidium
(4) Mycobacterium avium-intracellulare
(5) tumor (Kaposi sarcoma, non-Hodgkin's lymphoma)
Clinical features:
(1) presence of AIDS
(2) pain and tenderness in the right upper quadrant
(3) low grade fever
(4) elevated serum alkaline phosphatase (>= 2 times the upper limit of normal)
(5) variable elevation of total serum bilirubin
(6) evidence of 2 or more biliary lesions on ERCP or ultrasound
(7) exclusion of gallstones and inflammatory bowel disease
Biliary lesions may include:
(1) irregular thickening of the walls
(2) patchy dilatation
(3) strictures
(4) papillary stenosis
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Purpose: To evaluate a patient with AIDS for evidence of secondary sclerosing cholangitis (AIDS cholangiopathy).
Specialty: Gastroenterology, Surgery, general
Objective: criteria for diagnosis, complications
ICD-10: B23.8, K83.0,
