Description

Wagner et al developed an equation for predicting a dose of ethanol capable of producing a given blood concentration. The authors are from the University of Michigan.


 

Parameters:

(1) blood alcohol concentration in mg/dL at 2 hours after the exposure

(2) body weight in kilograms

 

estimated dose of ethanol in grams per kg =

= ((blood alcohol concentration in mg/dL at 2 hours) + 28.89) / 148.5

= (0.006734 * (blood alcohol concentration)) + 0.1945

 

estimated dose of ethanol in grams =

= (body weight) * (estimated dose of ethanol in grams per kg)

 

where:

• Ideally the fat free body mass should be used rather than the actual body weight. The study appears to have used young male volunteers.

• Calculating fat free mass can be done as outline if the previous section or it can be measured using bioelectric impedance.

• The volume of alcohol ingested can be estimated if the proof is known.

 

Limitations:

• Testing was done on male volunteers.

• The blood sampling is done 2 hours after the exposure. Adjustments would need to be made for specimens collected later.

• Ingestion of alcohol is often done over a period of time rather than a single bolus.

 


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