Description

Norman and Levy developed equations for adjusting a patient's Cornell voltage product. This improves the accuracy for diagnosing left ventricular hypertrophy. The authors are from the National Heart, Lung, and Blood Institute at NIH and the Framingham Heart Study.


 

Parameters:

(1) Cornell voltage product in mV•ms

(2) age in years

(3) body mass index (BMI) in kilograms per square meters

(4) gender

 

adjusted Cornell voltage product in mV•ms for males =

= ((Cornell volt product in mV•ms) + (1.8289 * (age)) + (19.0417 * (BMI)) - 360) / 2 =

= (0.5 * (Cornell voltage product)) + (0.9144 * (age)) + (9.5208 * (BMI)) - 180

 

adjusted Cornell voltage product in mV•ms for females =

= ((Cornell voltage product in mV•ms) + (3.2963 * (age)) + (18.1142* (BMI)) - 420) / 3 =

= (0.333 * (Cornell voltage product in mV•ms)) + (1.0988 * (age)) + (6.038 * (BMI)) - 140

 

where:

• The authors report the voltage product in mV•ms. The correct units may be mm•ms.

 

Performance (Table 6, Norman and Levy):

• An adjusted voltage product 1,572 mV•ms was 50% sensitive for detecting left ventricular hypertrophy.

• An adjusted voltage product 1,325 mV•ms was 85% specific for detecting left ventricular hypertrophy. An adjusted product 1,559 mV•ms was 95% specific.

 


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