Nicolaides et al developed an equation and nomogram for estimating the volume of donor blood required to transfuse in a fetus with erythroblastosis fetalis. The authors are from King's College Hospital in London.
Parameters:
(1) fetal hemoglobin
(2) donor blood hemoglobin (as packed red blood cells)
(3) adjusted fetoplacental blood volume based on week of gestation
where:
• The equation for estimating the fetoplacental blood volume is described in Chapter 2.
• Nicolaides provides a nomogram for a term "F". This is the inverse of ((15 - (donor blood hemoglobin)) / ((fetal hemoglobin) - 15)), which is multiplied by the fetal blood volume.
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