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Dusseldorf Score and Prognosis in Primary Myelodysplastic Syndromes

Purpose: To predict prognosis in patients with primary myelodysplasia using the Dusseldorf score of Aul et al.

Description

The Dusseldorf score can be used to predict prognosis in patients with primary myelodysplasia. It is similar to other scores except that it uses serum LDH as one of the scoring variables. It can be used to assign patients to risk-adapted treatment protocols.


Parameters:

(1) percent blasts in the peripheral blood

(2) hemoglobin in g/dL

(3) platelet count per µL

(4) serum LDH in U/L

 

Parameter

Finding

Points

percentage myeloblasts in the peripheral blood

>= 5%

1

 

< 5%

0

hemoglobin

<= 9 g/dL

1

 

> 9 g/dL

0

platelet count

<= 100,000 per µL

1

 

> 100,000 per µL

0

LDH

> 200 U/L

1

 

<= 200 U/L

0

 

Dusseldorf score =

= SUM(points for the 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

 

Dusseldorf Score

Clinical Group

Risk

5 year survival

0

A

low

53%

1 or 2

B

intermediate

26%

3 or 4

C

high

0%

 


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Specialty

Objective

ICD-10