Some drugs can cause hoarseness (dysphonia). Sometimes this is transient and of minor significance but sometimes it can indicate that a serious problem is present.
Cause of Dysphonia
Drug
vocal cord hematoma
anticoagulant (warfarin/coumadin), thrombolytic agent, phosphodiesterase-5 inhibitors, chemotherapy (thrombocytopenia)
chemical laryngitis
bisphosphonates
cough
angiotensin-converting enzyme (ACE) inhibitors
dry mucosa
anticholinergics, antihistamines, diuretics
hormone-related change
testosterone, danocrine
laryngeal dystonia
antipsychotics (including atypicals)
mucosal irritation
inhaled steroids, inhaled drugs of abuse
infectious laryngitis
inhaled steroids, immunosuppressants, chemotherapy (neutropenia)
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