Description

A variety of products have been developed to provide nicotine to a person trying to stop smoking. They can be effective when combined with other modalities. They lend themselves to unintended uses.


 

Products:

(1) transdermal patch (Nicoderm CQ, Glaxo Smith Kline)

(2) chewing gum (Nicorette, Glaxo Smith Kline)

(3) lozenge (Commit, Glaxo Smith Kline))

(4) inhaler (Nicotrol, Pfizer))

(5) nasal spray (Nicotrol NS, Pfizer)

 

Transdermal Patch

Patient smokes < 10 cigarettes per day

Patient smokes >= 10 cigarettes per day

21 mg patch (step 1)

NA

weeks 1-6

14 mg patch (step 2)

weeks 1-6

weeks 7-8

7 mg patch (step 3)

weeks 7-8

weeks 9-10

 

 

Chewing Gum

Patient smokes < 25 cigarettes per day

Patient smokes >= 25 cigarettes per day

Gum Dose

2 mg

4 mg

 

 

Lozenge

Patient first smokes <=30 minutes of waking

Patient first smokes >30 minutes of waking

Lozenge Dose

4 mg

2 mg

 

 

Week in Program

Number of Pieces Gum or Lozenge

1 to 6

1 piece q2h

7 to 9

1 piece q2-4h

10 to 12

1 piece q4-8h

 

 

Week in Program

Inhaler Dose

up to 12 weeks

6-16 cartridges per day

next 6-12 weeks

gradual reduction (weaning phase)

 

The nasal spray has a dose of 1 mg, given by taking 1 spray into each nostril (each spray 0,5 mg).

 

Nasal Spray

Parameter

duration of therapy

12 weeks

recommended dosing

1-2 doses per hour

maximum dose

5 doses in 1 hours

maximum dose per day

40 doses (2.5 per hour for 16 hours)

 

These products vary in cost, with the inhaler products reportedly more expensive.

 


To read more or access our algorithms and calculators, please log in or register.