A variety of products have been developed to provide nicotine to a person trying to stop smoking. They can be effective when combined with other modalities. They lend themselves to unintended uses.
Products:
(1) transdermal patch (Nicoderm CQ, Glaxo Smith Kline)
(2) chewing gum (Nicorette, Glaxo Smith Kline)
(3) lozenge (Commit, Glaxo Smith Kline))
(4) inhaler (Nicotrol, Pfizer))
(5) nasal spray (Nicotrol NS, Pfizer)
Transdermal Patch |
Patient smokes < 10 cigarettes per day |
Patient smokes >= 10 cigarettes per day |
21 mg patch (step 1) |
NA |
weeks 1-6 |
14 mg patch (step 2) |
weeks 1-6 |
weeks 7-8 |
7 mg patch (step 3) |
weeks 7-8 |
weeks 9-10 |
Chewing Gum |
Patient smokes < 25 cigarettes per day |
Patient smokes >= 25 cigarettes per day |
Gum Dose |
2 mg |
4 mg |
Lozenge |
Patient first smokes <=30 minutes of waking |
Patient first smokes >30 minutes of waking |
Lozenge Dose |
4 mg |
2 mg |
Week in Program |
Number of Pieces Gum or Lozenge |
1 to 6 |
1 piece q2h |
7 to 9 |
1 piece q2-4h |
10 to 12 |
1 piece q4-8h |
Week in Program |
Inhaler Dose |
up to 12 weeks |
6-16 cartridges per day |
next 6-12 weeks |
gradual reduction (weaning phase) |
The nasal spray has a dose of 1 mg, given by taking 1 spray into each nostril (each spray 0,5 mg).
Nasal Spray |
Parameter |
duration of therapy |
12 weeks |
recommended dosing |
1-2 doses per hour |
maximum dose |
5 doses in 1 hours |
maximum dose per day |
40 doses (2.5 per hour for 16 hours) |
These products vary in cost, with the inhaler products reportedly more expensive.
Specialty: Toxicology, Emergency Medicine, Critical Care
ICD-10: ,