Ivermectin (Stromectol, Merck) can be used to treat patients with strongyloidiasis or onchocerciasis.
Parameters:
(1) type of parasite (Strongyloides stercoralis vs Onchocerca volvulus)
(2) body weight of the patient in kilograms
(3) tablets strength (3 vs 6 mg)
Dosing: single oral dose
Dosing for Strongyloidiasis
|
Body Weight (kg) |
Dose for 3 mg Tablets |
Dose for 6 mg Tablets |
|
15 - 24 kg |
1 |
0.5 |
|
25 - 35 kg |
2 |
1 |
|
36 - 50 kg |
3 |
1.5 |
|
51 - 65 kg |
4 |
2 |
|
66 - 79 kg |
5 |
2.5 |
For body weights >= 80 kg, the dose is:
number of tablets =
= (body weight in kg) * (200 µg/kg) / (dose in mg per tablet) / 1000
Dosing for Onchocerciasis
|
Body Weight (kg) |
Dose for 3 mg Tablets |
Dose for 6 mg Tablets |
|
15 - 25 kg |
1 |
0.5 |
|
26 - 44 kg |
2 |
1 |
|
45 - 64 kg |
3 |
1.5 |
|
65 - 84 kg |
4 |
2 |
For body weights >= 85 kg, the dose is:
number of tablets =
= (body weight in kg) * (150 µg/kg) / (dose in mg per tablet) / 1000
Specialty: Infectious Diseases, Pharmacology, clinical, Gastroenterology
