Albendazole can be administered orally to treat patients with hydatid disease and neurocysticercosis.
Weight of the Patient
Oral Dose
Comments
< 60 kilograms
15 mg/kg/day divided for bid dosing with meals
maximum total daily dose 800 mg
>= 60 kilograms
400 mg bid given with meals
where:
• The dose of 800 mg a day is reached at 53.3 kilograms when dosed at 15 mg/kg. The dosing table given could be rewritten to use this as the cutoff point for patient weight.
Duration of therapy:
(1) neurocysticercosis: 8 to 30 days
(2) hydatid disease: 3 courses of therapy are recommended, with each cycle 28 days of therapy separated from the next cycle by a 14 day albendazole free interval
Patients with neurocysticercosis should also be considered for concurrent therapy with corticosteroids and/or anticonvulsants.
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