Talstad and Gjone reported a score for measuring ulcerative colitis disease activity. This can be used to evaluate the patient initially or to monitor the patient over time. The authors are from that National Hospital of Norway in Oslo.
Parameters:
(1) bowel movements per day
(2) body temperature
(3) heart rate
(4) body weight
(5) colon on X-rays
(6) proctoscopy
(7) erythrocyte sedimentation rate (ESR)
(8) hemoglobin
(9) white blood cell count
(10) platelet count (thrombocytes)
(11) total protein
(12) serum albumin
(13) serum iron
(14) total iron binding capacity (TIBC)
(15) Schilling test (for vitamin B12 absorption)
(16) serum folic acid
Parameter |
Finding |
Points |
---|---|---|
bowel movements per day |
0 to 2 |
0 |
|
3 to 5 |
1 |
|
6 to 10 |
2 |
|
> 10 |
3 |
body temperature |
< 38°C |
0 |
|
38 to 39°C |
1 |
|
> 39°C |
2 |
heart rate |
<= 100 beats per minute |
0 |
|
> 100 beats per minute (tachycardia) |
2 |
body weight |
< 5 kg weight loss |
0 |
|
5 to 10 kg weight loss |
1 |
|
> 10 kg weight loss |
2 |
changes in colon on X-ray |
normal |
0 |
|
mild |
1 |
|
moderate |
2 |
|
severe |
3 |
|
toxic megacolon |
4 |
proctoscopy |
normal |
0 |
|
mild to moderate |
1 |
|
severe |
2 |
ESR |
< 10 mm/h |
0 |
|
10 to 30 mm/h |
1 |
|
> 30 mm/h |
2 |
hemoglobin |
> 11.8 g/dL |
0 |
|
10 to 11.8 g/dL |
1 |
|
< 10 g/dL |
2 |
white blood cell count |
<= 10,000 per µL |
0 |
|
> 10,000 per µL |
2 |
platelet count |
<= 400,000 per µL |
0 |
|
> 400,000 per µL |
2 |
total protein |
>= 6.5 g/dL |
0 |
|
5.5 to 6.4 g/dL |
1 |
|
< 5.5 g/dL |
2 |
serum albumin |
>= 3.3 g/dL |
0 |
|
2.5 to 3.2 g/dL |
1 |
|
< 2.5 g/dL |
2 |
serum iron |
>= 70 µg/dL |
0 |
|
50 to 69 µg/dL |
1 |
|
< 50 µg/dL |
2 |
TIBC |
>= 270 µg/dL |
0 |
|
200 to 269 µg/dL |
1 |
|
< 200 µg/dL |
2 |
Schilling test |
normal |
0 |
|
defective vitamin B12 absorption |
2 |
folic acid |
>= 3.0 ng/mL |
0 |
|
< 3.0 ng/dL |
1 |
where:
• The upper limit for a normal platelet count may be > 400,000 per µL.
total score =
= SUM(points for all 16 parameters)
Interpretation:
• minimum score: 0
• maximum score: 34
• The higher the score the greater the activity of the ulcerative colitis.
Purpose: To evaluate disease activity in a patient with ulcerative colitis using the score of Talstad and Gjone.
Specialty: Gastroenterology
Objective: severity, prognosis, stage, disease progression
ICD-10: K51,