Criteria for patient selection:
(1) transient neurologic signs and symptoms
(2) abnormalities seen on MRI
The differential diagnosis includes:
(1)
stroke-like migraine attacks after radiation therapy (SMART)
(2) familial/sporadic hemiplegic migraine (FHM/SHM)
(3) posterior reversible encephalopathy syndrome (PRES)
(4) mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS)
(5) status epilepticus (SE)
(6) meningoencephalitis
(7) vasculitis
(8) radiation vasculopathy
(9) cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
where:
• Paraneoplastic neurologic syndromes would be included under meningoencephalitis.