Delusional jealousy (Othello Syndrome) is a rare disorder with the patient convinced of a spouse's or companion's infidelity.
Features:
(1) intense jealousy often with belief of infidelity
(2) often associated with paranoia
(3) present despite contradictory evidence
Conditions associated with delusional jealousy:
(1) schizophrenia
(2) psychosis
(3) alcohol-related dementia or psychosis
(4) other forms of dementia
(5) Parkinson's disease with dementia or associated with dopaminergic therapy
(6) frontal lobe disorder (tumor, etc)
Differential diagnosis:
(1) exaggerated or pathological jealousy associated with disordered self-esteem
A patient with delusional jealousy may become violent and kill their spouse.
