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Definitions of Donor Reactions of Goldman et al: Apheresis-Related

Description

Goldman et al defined the reactions and complications that can affect donors. This can help to standardize the surveillance of complications. The authors are from the Canadian Blood Services, Blood Systems Inc (Scottsdale), Hema-Quebec, and the Dutch National Hemovigilance Office.


 

Categories of donor complications:

(1) local symptoms (A)

(2) generalized symptoms, vasovagal reactions (B)

(3) related to apheresis (C)

(4) allergic reaction (D)

(5) other serious complication (E)

(6) other, major cardiovascular event (F)

 

Complications associated with apheresis:

(1) citrate reaction, with hypocalcemia causing neuromuscular hyperreactivity

(2) hemolysis

(3) air embolism

(4) infiltration of intravenous saline

 

Other reactions (local, generalized, etc) may also affect the aphersis donor.

 


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