African trypanosomiasis may be associated with a number of cutaneous lesions that can be important clues to the underlying infection.
Skin changes associated with African trypanosomiasis:
(1) trypanoma (inflammatory nodule) or chancre at the inoculation site during the primary phase
(2) erythematous rash (trypanid rash) during the hemolymphatic stage which may be annular, macular or papular. The rash tends to start on the trunk and may show centrifugal spread.
(3) transient cutaneous edema, especially of the face
(4) mild pruritis
A patient who is being treated for African trypanosomiasis may also develop drug-induced skin lesions.
To read more or access our algorithms and calculators, please log in or register.
