Criteria of the European Organization for Research and Treatment of Cancer Groupe d'Eude des Lymphomes de l'Adulte (EORTC-GELA) for Favorable Prognostic Groups of Hodgkin's Disease
The European Organization for Research and Treatment of Cancer and Groupe d'Eude des Lymphomes de l'Adulte (EORTC-GELA) have identified prognostic factors associated with favorable and very favorable outcomes in patients with Hodgkin's disease. This can help determine how intensive of a therapeutic regimen is required for management.
Parameters
Very Favorable: all of the following
Favorable: all of the following
age
< 40 (16 – 39)
< 50 (16 – 49)
gender
female
male or female
Clinical Stage (Ann Arbor)
I
I or II
B symptoms
none (clinical A)
(see ESR)
histology
lymphocyte predominant or nodular sclerosing
lymphocyte predominant or nodular sclerosing
erythrocyte sedimentation rate (ESR)
< 50 mm in first hour
ESR < 50 AND no B symptoms; ESR AND B symptoms present
bulky disease
absent
absent
number of lymph node regions involved
1 (definition of CS I)
< 4
where:
• Criteria for Ann Arbor staging and clinical symptoms are given above, under non-Hodgkin's lymphoma.
• The gender for the favorable group was not specified, but males are listed in Table 1, page 1732 of Wilder et al.
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