Rodriguez listed characteristic findings seen in an autoimmune disorder. The author is from the Mayo Clinic.
Criteria for an autoimmune disorder:
(1) The disease is associated with a precise autoantigen.
(2) The disease can be experimentally induced in animals by immunizing them against the autoantigen.
(3) Administration of the autoantibody or autoreactive T cells can induce the disorder in normal animals.
(4) The autoantibody or autoreactive T cells can be isolated from lesions.
(5) Disease activity correlates with the level of autoantibody or autoreactive T cells in the blood.
(6) The disorder is associated with other autoimmune disorders. (A person with the disorder is more likely to have one or more other autoimmune disorders.)
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