McLeod et al identified inappropriate prescription practices for older adults in Canada. Certain prescriptions should be avoided in general practice. The authors are from McGill University in Montreal.
Disorder
Drug
Comorbid
Reason
peptic ulcer
cimetidine
warfarin
bleeding
irritable bowel syndrome
anticholinergic drugs
dementia
cognitive and behavioral problems
irritable bowel syndrome
antispasmodic drug
dementia
cognitve and behavioral problems
diarrhea
diphenoxylate, long-term
drowsiness, cognitive impairment, dependence
muscle spasms
cyclobenzaprine or methocarbamol
drowsiness, agitation, disorientation
COPD
corticosteroids, long-term
diabetes
worsen diabetes
stroke prevention
dipyridamole
ineffetive
extrapyramidal effects of anti-psychotic drugs
anticholinergic drug
agitation, delirium, impaired cognition
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